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Three main types of cells comprise the skin: epidermal, dermal, and hypodermal. Epidermal cells are found in the epidermis, the top layer of the skin. These cells include keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Keratinocytes are the most abundant – they produce keratin to waterproof the skin and create the outer protective skin barrier. Melanocytes produce melanin, which gives skin its pigmentation and protects it from UV rays.

The dermis is beneath the epidermis and consists of collagen-producing fibroblasts, macrophages, mast cells, blood vessels, sweat glands, and hair follicles—strength and elasticity to the skin. The deepest is the hypodermis, composed mainly of adipocytes (fat cells). This subcutaneous tissue acts as an insulator and shock absorber. Together, these multiple skin cell types regenerate constantly to replace dead surface cells and keep the skin functioning as a protection for the body.

Types of Skin Cell

Epidermal cells: These are the outer layer of skin cells. The main types are:

Keratinocytes – The most abundant type, they produce keratin, which helps the skin remain waterproof.

Melanocytes – Found in the down layer of the epidermis, they produce melanin, which gives skin its color and protects it from UV damage.

Merkel cells – Mechanical sensory cells that detect pressure and textures.

Langerhans cells – Immune system cells that help protect against pathogens and potential threats.

Dermal cells: These are found in the dermis layer below the epidermis.

Fibroblasts – The most common cell type, they produce collagen, elastin, and ground substance to give skin flexibility and strength.

Adipocytes are fat storage cells that provide cushioning and insulation under the skin.

Mast cells – Immune cells are involved in allergic reactions and wound healing.

Blood and lymph vessels carry oxygen, nutrients, and waste products to and from the skin tissues.

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